SARS-CoV-2 S1 (RBD) Delta B.1.617.2 (India), GFP/His-Tag Purity >95%

SARS-CoV-2 S1 (RBD) Delta B.1.617.2 (India), GFP/His-Tag Purity >95%Recombinant protein of the receptor binding domain (RBD), Mutant (L452R T478K) of SARS CoV 2 (COVID 2019) Spike S1 from Wuhan pneumonia virus with C terminal His GFP Tag. The mutations L452R T478K are characteristic for the fast spreading SARS CoV 2 virus variants B. 1. 617 emerged in India. These mutations are affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors and enter them. Due to

In the process of pseudouridine degradation

"green" indicates fusion of the protease to green fluorescent protein (GFP)

SNKLDSKVSGNYNYLYRLFRKSNLKPFERDISTEIYQAGNKPCNGVAGFNCYFPLRSYSF

Cystatin C is a useful biomarker for assessing kidney function

including dendritic cells

This increase is most likely due to a higher binding affinity of the spike protein to hACE2

TEV cleavage results in two cleavage products of 42

Indian Variant

Sequence without tags (AA 1-306):SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ

Binding of wild-type spike RBD to the membrane of ACE2 overexpressing cells

and Pingnian He Patients with diabetes infected with COVID-19 have greater mortality than those without comorbidities

: P2020-116